Key steps to active longlivety in the KME system.

The path to active longevity is a systematic, consistent and regular care of one's health. Implementation of the project "Active Longevity" implies the need to compile and implement a personal program for monitoring, maintenance, and correction of health. On the path of developing and promoting the project "Active Longevity", KME allows regular assessment of the state of a person's body and correction of the functions balance of all its systems.

Assessment of the state of the body's functional systems.

The human body is a single (whole) organism, the functions of which is provided and supported by various functional systems (nervous, cardiovascular, digestive, immune, endocrine, etc.). Organ systems do not work in isolation from each other but are integrated to ensure the combined life activity of the whole organism. Human health and life expectancy depend on the normal operation of each functional system. The rate with which aging occurs in each of these systems is not the same and has no uniform rule. It is individual for each person. There is physiological aging caused by a gradual decrease of all body functions with age. It happens while work capacity and general activity can be other preservation for a long time. There is also pathological aging resulting from various pathological states of the body that make the aging process uneven, accelerate wear and tear, and speed the aging process itself. Premature aging of the human body is directly connected with changes in the balance of the processes occurring in it. KME makes it possible to evaluate the functional state of each of these systems.

  • Assessment of the state of organs and tissues within functional systems.

    Each functional system includes specific organs and tissues that determine how it works. For example, the digestive system consists of the intestine, liver, stomach, etc. The KME allows you to assess the condition and function of each of these comprising organs.

    • Tissue metabolism

      Each organ's tissue consists of specialized cells and the external environment in which they live and function. This environment is called the extracellular matrix. The rate of metabolic processes in an organ is determined by the degree of functional activity of this organ's cells and the extracellular matrix.

      • Extracellular matrix.

        The extracellular matrix (ECM) is a highly specific environment characteristic only of a particular organ's cells. The ECM provides the cells of the organ with nutrition through the blood capillaries that permeate the matrix. Tissue metabolites (products of the organ cells) are excreted through the ECM through the venous and lymphatic capillaries. The matrix also provides regulatory interactions between the cells of this organ. Regulatory signals controlling cell functioning are transmitted through the ECM. Disturbance of the matrix structure and function is at the root of all diseases and the body's aging.

      • State of the vascular system of the matrix.

        Vessels in the matrix are represented by arterial, venous, and lymphatic capillaries. Through the arterial capillaries in the matrix, cells receive nutrition. Thanks to the work of the venous and lymphatic capillaries, cellular metabolites and toxins are removed from the matrix. The state of the vessels penetrating the matrix affects both the ECM's function and all cells' function.

      • The nutritional function of the extracellular matrix (cell nutrition).

        Arterial capillaries in the matrix provide nutrients and oxygen for the vital functions of cells. Impaired arterial microcirculation leads to decreased nutrition supply to the tissue of an organ.

      • Drainage function of the ECM.

        Lymphatic and venous capillaries provide the drainage function of the matrix (removal of metabolites and toxins). Through the arterial blood, not only cells’ nutrients can enter the matrix, but also exogenous (external) toxins. There are also waste products of cells that can contain endogenous (internal) toxins. Most of the toxins, endogenous and exogenous, accumulate and deposit in the matrix, creating an overall toxic load on a specific organ or the body as a whole. Disruption of the organ tissue's drainage system leads to toxins accumulation in it and the risk of development of diseases.

      • Regulatory and communicative function of the ECM.

        Through the blood’s arterial capillaries, various regulatory molecules, such as hormones, enzymes, immunoglobulins, etc., enter the matrix. At the same time, tissue cells produce their regulatory molecules (cytokines, growth factors, etc.). The state of the matrix's normal structure (i.e., normal tissue morphology), the absence of toxins in the matrix ensure the optimal functional activity of regulatory molecules in the tissue. In the KME system, it is possible to assess the state of all matrix functions and subsequently correct them.

    • Intracellular metabolism.

      A particular function of an organ is sustained by the level of vital activity of its cells.

      • Assessment of the energy function of a cell.

        The cell's energy function is supplied by the cell's own "energy stations" called mitochondria. With age and ailments, the number of mitochondria inside each cell decreases significantly. Disruption of mitochondria can lead not only to the interruption of the overall function of a cell but also to the cell’s demise.

      • Assessment of the state of intracellular synthesis (synthetic function of the cell).

        The cell synthesizes (produces) a large number of different substances to ensure organ function. The cell's synthetic function depends both on the cell's energy and on the correct sequence of its functioning. Any change in intracellular synthesis affects the function and structure of the organ itself, as well as the quality and quantity of the functional molecules it produces.

      • Assessment of the state of the excretory function of the cell.

        A large amount of "broken" molecules accumulate inside the cell in the course of its work. These accumulations disrupt the normal cellular function and are intracellular toxins. The cells have a mechanism for getting rid of such a "broken waist". This process of intracellular drainage, purification is called autophagy. Controlling the state of autophagy is an essential criterion for maintaining the optimum state of the cell.

      • Assessment of the protective function of the cell.

        The work of each cell is aimed at performing and maintaining the function of the whole organ. Nature has provided a mechanism for getting rid of non-functional cells and replacing them with new, functional ones. In a normally functioning organ, old and poorly performing cells are eliminated by the mechanisms of apoptosis. Apoptosis is a natural process of controlled cell death to provide space for young cells. Using the KME system, it is possible to assess the state of intracellular metabolism and conduct apoptosis correction.

  • Assessment of the state of the nervous system.

    With the KME system's help, it is possible to assess the autonomic nervous system's (ANS’s) function based on the balance of the sympathetic and parasympathetic nervous systems. The function of the central nervous system (CNS) can be assessed by the functional state of the nerves and various brain structures. The KME allows assessing the functional state of the primary brain structures.

    • Own systems of neuronal regulation.

      Nerves of the internal organs and brain structures are interconnected through regulatory molecules (signals) in the form of neurotransmitters, neuropeptides, neuromodulators, and neurohormones. These molecules provide all of the body's many functions. The KME system helps in evaluating the activity of neurotransmitters, neuropeptides, neuromodulators, neurohormones in the mechanisms of functional correction.

  • Assessment of hormonal balance.

    The hormonal balance of the human endocrine system is determined by the functioning of the organs and glands of the endocrine system itself and by regulatory molecules from the brain structures. Therefore such regulation is often called neurohumoral. Premature aging of the human organism is directly related to a change in the balance of hormones in the body.

  • Assessment of the body's immune status.

    The human immune system is an integrative system that involves various organs and tissues. Its function manifests throughout the body. There are various criteria and markers in the KME system to assess the state of the immune system.

    • Inflammatory processes.

      An inflammatory process helps to maintain the protective function of the immune system. A chronic inflammatory process becomes pathological. The KME system makes it possible to assess the severity and depth of inflammatory processes and the body's immune response.

    • Sluggish inflammatory processes.

      Sluggish and chronic inflammatory processes reduce the functional activity of organs and tissues. These processes are characterized by a long-term decrease in the immune response and its polymorphism.

  • Assessment of the psychological state.

    A person's psychological state manifests itself not only in his/her emotional condition but is also reflected in his/her health and social adaptation ability. The KME system helps to reveal connections between the personal psychological characteristics of an individual and his relations with society; influences of these processes and activities in the living environment, as a result, reflected on the functional state of his/her health.

Assessment of the psychological state.

The psychological state of man is not only evident in its emotional situation, but also affects health and social adaptability. The KME system is suitable to determine the connection between the individual psychological characteristics of humans and their social attitude as well as influence on the processes of life activity that affect the function of its health.

  • Reactions to external and internal psychological factors.

    A person's thoughts, attitudes, and habits determine his/her internal psychological state. Interaction with society and one's reactions to it determine a person's psycho-emotional response to these emerging external factors. External factors may include: Natural factors include the length of daylight hours, the environment's temperature regime, and other geophysical factors. Social factors such as relationships with family members, colleagues, friends, living conditions, employment, socio-economic and political, cultural formation of society. Internal factors can include character traits, personality qualities, mood, emotions, habits, mind, will, features of the reaction of the nervous system.

  • Degree of stress - loads

    Inconsistency between the "desired and actual" in a person’s own assessment of events and thoughts can create a conflict situation, accordingly experiencing a degree of stress. Loss of control over the situation, personal self-esteem, inability to achieve ambitious goals, etc., can also be attributed to these factors that create stress load. The depth and duration of these conditions determine the degree of psychological burden.

  • Formed psychological programs

    The internal and external psychological attitudes formed in society's perception of oneself and interaction with it are "formed" (induced) psychological programs. Such programs include, for example, a sleep program, an intellectual program, a learning program, programs of development of creative abilities and situational modeling, etc.

  • The main reasons for the formation of the depressive states

    Depressive states affect the physical condition of the body, mood, and psyche - they are not only a reduced emotional state of a person but also altered biochemical processes in the human body that can harm mental and physical health. Mood swings, tension, sleep disturbances, and apathy are just some of the signs of depression. People with depression often have low self-esteem, have a passive attitude towards life, and exhibit increased anxiety. Often, the causes of these conditions are associated with increased emotional instability, complicated relationships with others, financial problems, forced lifestyle changes, and general stress loads. A KME specialist can help a person to: recognize negative thought patterns, understand problems, learn how to find joy and pleasure from their activities, get rid of behavioral stereotypes, set realistic goals and objectives for themselves, set priorities in their plans, be among people, and participate in social and other activities that can lift a person’s spirits.

  • Formed mechanisms of psychological defense

    The formed psychological defense mechanisms can be compared to other, similar in nature, defense mechanisms in the human body. These mechanisms include the immune reactions, nervous system reactions, and protective role of adaptation reserves.

In the KME system, there is a possibility for integrative assessment of a person's psychological state according to the listed above issues and their subsequent compensation.

Recommendations for correction of traditional methods and components of a healthy lifestyle (HLS).

To maintain and restore the body's metabolic balance, traditionally, the following correction determined by the selection applied: food, vitamins, micro-macro nutrients, activation of the body's own drainage functions, muscle exercise (to balance the necessary motor and muscular activity).

  • Food products

    The importance and role of proper food selection is a well-known fact. The individual approach to food consumption has a significant contribution to the HLS and Anti-aging programs. Foods provide vital functions:

    1. Ensuring the development and continued functioning of cells and tissues (the plastic role of food);
    2. Providing the energy needed to replenish the body's energy demands at rest and during all physical activity (energy role of food);
    3. Providing substances from which regulators of metabolic processes are formed: enzymes, hormones, and others.
    • Products that support activate or slow down the metabolism

      Both excessively increased and excessively decreased metabolism can affect the body's overall metabolism. The activation and deceleration of metabolic processes with the help of foods is strictly individual in nature. The selection of foods in the KME system is based on several key components of the overall metabolic process. KME makes it possible to assess which substances (proteins, fats, or carbohydrates) are most involved in metabolism at the moment and the degree of their activity.

  • Selection of necessary micro-and macro-nutrients, vitamins

    The selection of necessary micro-and macronutrients makes a significant contribution to maintaining metabolic balance in the body.

    • Vitamins

      Many vitamins are synthesized independently in the human body. The balance of the human body's own vitamins is often disturbed. This reflects in a wide variety of metabolic functions. With the help of the KME system, it is possible to analyze the body's need for nutrients, as well as those functional processes that depend on the lack of specific vitamins and trace elements.

    • Micro-, macro elements

      Micro-macro-nutrients are the source of synthesis of the body's own vitamins. They participate in the formation of tissue structures, and in ionic form, determine the energy and metabolic function of all cells of the body. An imbalance of micro-macro-nutrients can be the basis for metabolic disorders and the formation of pathologies.

  • Drainage (excretory function of the body), removal of excess and toxic metabolites

    The human body, at different levels of its organization, has excretory systems that ensure the maintenance of metabolic functions. The degree of excretory systems activity (drainage) allows maintaining the expected level of tissue and cellular metabolism, freeing tissues from excessive metabolites and toxins.

  • Recommendations on physical activity

    Muscle tissue takes part in all human movements. It helps to move blood through blood vessels, food through the digestive tract, metabolic products through the urinary tract, glandular secretions through the ducts, etc. Muscle load recommendations in the KME system consider the need for increased or decreased muscle function to maintain optimal tissue metabolism.

The possibility of functional correction of the balance of physiological and psychosomatic processes using the method of "compensation" in the KME system.

"Compensatory correction" with the application of the KME system for restoration of physiological and psychosomatic processes balance is based on the effect of the interrelation of activity of biophysical processes reflected in their electric fields. Compensation in KME aims to correct a balance of the electric field of the process, which is in interrelation with the physiological process. This type of correction has no adverse effect on the physiological function and, due to its informational content and action, does not introduce anything alien to the source, providing only the task of "targeting" for self-restoration of the normal physiological function. The compensatory correction method has a selective local action character and can be applied for simultaneous correction of several processes.

Theortical foundations of physical and mathematical medicine

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